The preferred antihypertensive drugs for renal insufficiency are angiotensin-converting enzyme inhibitors, calcium antagonists and so on. 1. Angiotensin-converting enzyme inhibitors: they are drugs that inhibit vasoconstriction and improve blood circulation. It has a dilating effect on the glomerular arteries and reduces the intra-glomerular pressure, which is less burdensome to the kidneys, and these drugs include captopril, enalapril, and so on. 2. Calcium ion antagonists: By regulating the ion levels inside and outside the cell, they inhibit the contraction of cardiomyocytes and dilate blood vessels. It can also antioxidize and reduce the damage of hydroxyl to the kidney. These drugs include nifedipine controlled-release tablets, felodipine extended-release tablets and so on. When a patient has hypertension combined with renal insufficiency, he must use the medication strictly and regularly under the guidance of the doctor, and cannot reduce or stop the medication on his own to avoid aggravation of the condition. Regular review is also needed to closely monitor the health condition.