What causes pain in the legs and feet of diabetics? This is a question that many diabetic patients or their families consult to. For example, in the pain department, we often encounter diabetic patients who go for consultation and treatment, asking what medicine can relieve them. Afterwards, the doctors in the pain department or other departments will advise the patients to be referred to a diabetic foot specialist. Because, these are likely to be the early symptoms of diabetic foot. Long-term hyperglycemia in diabetics can cause some damage to the patient’s blood vessels. Some patients also have hypertension and hyperlipidemia, which can cause the accumulation of “garbage” in the lumen of the arteries of the lower extremities, resulting in smaller lumen, thicker vessel walls, blocked blood flow, and in some cases, even serious occlusion, resulting in ischemia of the lower extremities. This time, it will give the patient a certain amount of pain. Therefore, for this pain of diabetic patients, due to the complexity of the cause of lower limb vascular lesions and the special nature of diabetic patients, some departments simply can not treat this disease, and do not dare to accept such patients, because the slightest failure, the ischemic limb began to infection, ulceration, necrosis, amputation, and even crisis patients’ life safety are possible. Moreover, the patient’s lower limbs are more vulnerable at this time, and their resistance and immunity are weakened. For example, we admitted a patient from Hunan who went to a health care store doing fire therapy because of pain in his legs and feet, and ended up burning both feet. Later, he faced amputation due to improper treatment, and the patient confessed that he “felt like waiting for death”! So, when diabetic patients have leg and foot pain, do not go to the point to buy some random painkillers, or go to some health stores ah small clinics ah, but to the hospital to do the relevant diagnosis, especially to check whether the blood vessels are through. If it is the early symptoms of diabetic foot, we should treat the symptoms in a timely manner to avoid serious consequences and harm to the patient.