If the patient has the symptom of fever and kidney pain, it is most likely that he/she has acute pyelonephritis. Acute pyelonephritis is a kind of urinary tract infection, belongs to the upper urinary tract infection, and is a more serious urinary tract infection. When the bacteria infects the renal pelvis, it produces inflammation locally, which will stimulate the patient to produce kidney pain symptoms, accompanied by fever. In some cases, the attack may be preceded by chills. If acute cystitis occurs, it may be accompanied by frequent urination, urgency, and painful urination. Although acute pyelonephritis can be quite acute and the symptoms can be quite severe, most people get better when they are given anti-infective treatment. The best antibiotics for this infection are cephalosporin antibiotics, penicillin antibiotics and quinolone antibiotics, such as ceftriaxone, penicillin sodium for injection and moxifloxacin. During the anti-infection treatment, it is important to drink plenty of fluids and urinate regularly, as this will promote healing.