Sleeping at night with a sore calf stomach, usually the following factors: First, the most common factor is too much exercise the day before, or too much glycolysis in the body to release a large number of ATP at the same time, will lead to the body to produce too much lactic acid, lactic acid will be in the legs, especially in the relatively more developed muscles of the zone aggregation, which leads to calf tummy soreness. Second, heat stroke heat cramps, heat exhaustion and pyrexia at the same time, there will be rhabdomyolysis, but also in the evening when sleeping calf stomach soreness. Third, the incorrect way and method of exercise, there will also be excessive accumulation of creatine kinase in the body leading to calf soreness. Fourth, calf contact with a large number of allergens history, resulting in local skin allergies, there will be soreness and pain in the calf stomach. Fifth, infections such as retrograde blood infections, peripheral infections, dengue or cellulitis can also occur when sleeping with soreness and pain in the calf tummy.