Blisters in the mouth are often considered to be caused by food allergies, herpes virus infection or oral ulcers, etc. Patients can take antihistamines, antiviral drugs or broad-spectrum antiseptic drugs according to the different causes of treatment. 1. Food allergy: If there is an allergy after eating certain food, it may lead to a metamorphic reaction in the mouth, thus leading to blisters in the mouth, and patients can take antihistamines such as loratadine and chlorpheniramine for treatment. 2. Herpes virus infection: If it is caused by herpes simplex virus infection, viral infectious stomatitis, such as herpes stomatitis and recurrent herpes, there are clusters of blisters on the gums. It can be treated with oral antiviral drugs such as acyclovir and pentoxifylline. 3. Mouth ulcers: mostly due to the lack of vitamins or infections and other reasons, patients will appear in many places of the mouth and tongue erosion sores, sores red and swollen and other symptoms, patients can take quinclorac and other broad-spectrum antiseptic drugs such as tablets for treatment. If the patient’s mouth blisters, it is recommended that timely medical diagnosis, and under the guidance of the doctor reasonable medication, to avoid unauthorized use of drugs on the body to cause adverse effects.