Thrombocythemia that has been cured still has the possibility of recurrence, but the specific situation should be determined by the doctor according to the different conditions and the individual’s physical condition after consulting a doctor. Thrombocytosis is broadly categorized into primary thrombocythemia and secondary thrombocythemia. 1. Primary Thrombocythemia: 50% to 70% of the patients are due to genetic mutation, the disease progresses slowly, it is a benign disease process, the current treatment is a long-term remission treatment, and cannot really achieve a cure, so after stopping the drug (hydroxyurea, aspirin), the probability of relapse exists. If such a situation occurs, please consult a doctor in time for standardized diagnosis and treatment. 2. Secondary thrombocythemia: it is due to other disease factors, such as general chronic inflammatory diseases, resulting in thrombocythemia, after timely medical treatment of the primary disease for complete cure (such as levofloxacin anti-infection), thrombocythemia will improve or even return to normal. Re-recurrence is mostly caused by other primary diseases, and as long as the primary disease is controlled, the likelihood of thrombocytosis will decrease. If relapse occurs, please consult a doctor for standardized treatment in time to prevent irreversible damage to the organism.