In general, statins do not have the effect of raising globulin, so taking statins will not raise globulin. Statins are commonly used as lipid-lowering drugs in clinical practice, commonly used in the treatment of hyperlipidemia, atherosclerosis, etc. Commonly, there are simvastatin, atorvastatin calcium and so on. Its contraindications are: severe hepatic and renal insufficiency, drug allergy, pregnancy, lactating women and so on. Adverse reactions are increased liver enzymes, muscle soreness, rhabdomyolysis and so on. Generally speaking, statin lipid-lowering drugs do not have the effect of elevating globulin, and the possible causes of globulin elevation include acute and chronic hepatitis, autoimmune diseases, etc. It is necessary for the clinician to conduct further examination to clarify the cause of the disease, to receive professional treatment, and to be guided by the doctor as to whether or not it is necessary to discontinue the use of the statin drug or to adjust the dosage of the statin drug.