Coronary heart disease is a common disease that seriously endangers people’s health, patients generally need to take long-term medication to control the disease, the process of drug control, must be reasonable medication, however, many patients with coronary heart disease are arbitrary, indiscriminate use of drugs, and even take it for granted to stop the drug. 1, long-term use of insulin (propranolol) of coronary heart disease patients should not suddenly stop the drug. Otherwise, there will be sympathetic hyperexcitation, resulting in panic, cardiovascular ischemic changes and other clinical manifestations, and even exacerbate the occurrence of angina pectoris, inducing myocardial infarction. 2, nitroglycerin do not stand to take. When angina attacks, patients should immediately take a nitroglycerin under the tongue, or chewed and contained under the tongue, at this time do not stand in a standing position to take, but should sit on a wide chair, so as not to fall and faint. If it is not effective, you can use it again after 15 minutes. Do not take more than two tablets at the same time, or use it repeatedly. This is because nitroglycerin has a strong vasodilating effect and a strong instantaneous hypotensive effect, so it is easy to induce postural hypotension when the blood pressure is relatively low. 3, don’t take Chinese medicine indiscriminately. The heart is a kind of Chinese medicine that can make the heart pacing point or conduction system function better and speed up the heartbeat, so avoid using it when the heartbeat is too fast. The heart pills and the heartbeat pills have a slow heartbeat effect, so patients with a slow heartbeat should be careful. 4, coronary heart disease patients with glaucoma, use with caution or avoid using nitroglycerin. Nitrate drugs can dilate small arteries and veins, resulting in increased atrial aqueous production in the anterior chamber of glaucoma patients, reduced drainage and increased intraocular pressure. 5, unauthorized addition or reduction of combined medication is not advisable. Some patients with coronary artery disease are eager to cure the disease and take it upon themselves to increase the amount of medication, which may lead to drug poisoning. Other patients once the condition is relieved, the unauthorized reduction, but the risk of myocardial infarction is very high, once the rescue is not timely, it may instantly kill. There is also a great danger in combining drugs at your own discretion, because the interactions between coronary heart disease drugs are extremely complex, so be sure to follow medical advice to increase or decrease the dosage.