How to get rid of multiple stones in both kidneys, a comprehensive evaluation must be made before deciding how to proceed. First of all, ultrasound examination must be done to determine the size, location and hydronephrosis of multiple stones in both kidneys. At the same time, it is also necessary to do an assessment of kidney function, if the multiple stones in both kidneys are less than 0.5cm, this situation is generally through drinking more water, taking stone removal drugs, and appropriate exercise, the stones can be discharged from the body. If the stone is larger than 0.5cm and smaller than 1.0cm, it is recommended to consider extracorporeal shock wave lithotripsy, which breaks up the stone through extracorporeal shock wave lithotripsy and then discharges it from the body. If the stone is bigger, it needs to be treated by ureteral flexible mirror or percutaneous nephrolithotomy surgery.