No tuberculosis can not take tuberculosis drugs, but for close contacts of open tuberculosis, depending on the situation, can be isoniazid prevention, anti-tuberculosis drugs should be strictly in accordance with the doctor’s prescription medication. Commonly used anti-tuberculosis chemical drugs include isoniazid, rifampicin, pyrazinamide, ethambutol, etc. These drugs can have different degrees of side effects, which can have some impact on human health. Therefore, patients who have not been diagnosed with tuberculosis are generally not recommended to take tuberculosis drugs. Isoniazid is prone to liver damage and liver function needs to be checked regularly before and during the course of medication. Patients without tuberculosis who overdose on their own may experience convulsions, confusion, coma, and other symptoms, and acute hepatic necrosis may occur if not treated promptly. Rifampicin has hepatotoxicity, if used in combination with other tuberculosis drugs, hepatomegaly and jaundice can occur. While pyrazinamide may cause arthralgia, ethambutol may cause side effects such as optic nerve damage, and ethambutol can cross the placenta, which may lead to fetal malformations when self-administered by pregnant and lactating women. For close contacts of open tuberculosis, isoniazid prophylaxis may be administered as appropriate, but the drug must be administered under the guidance of a medical professional. Patients with tuberculosis should follow the doctor’s instructions to use the medication in full dosage and regimen, but people without tuberculosis should avoid the use of anti-tuberculosis drugs to avoid serious adverse reactions or other effects.