Normal urine routine can not completely exclude kidney disease. Urine routine mainly monitors urine protein, red blood cells, white blood cells, urine specific gravity, urine sugar, pH, tubular pattern, crystals, microorganisms, etc.; under normal circumstances, normal urine routine indicates that there may be no inflammation in the urinary system, glomerular filtration function, tubular concentrating and reabsorption function is generally normal, but normal urine routine can not completely exclude kidney disease. Some kidney disease can be negative urine test, no proteinuria, hematuria, but only manifested by abnormal renal function, elevated blood creatinine, such as renal interstitial tubular function damage, renal vascular disease. And urine routine test sensitivity is limited, there may be false-negative results. To determine whether there is kidney disease, other related tests such as 24-hour urine protein quantification, renal function, renal ultrasound, etc., according to the results of the examination to make further judgments on the type of disease, and if necessary, can be carried out by renal puncture biopsy to clarify the type of disease. It is recommended that patients with suspected kidney disease should go to regular hospitals in time, complete relevant examinations as prescribed by the doctor, make a clear diagnosis, and take active symptomatic treatment.