Smallpox is chickenpox, which is a viral skin disease caused by chickenpox-herpes zoster virus infection, and can be removed by wet compresses, topical medications, and oral medications. 1. Wet compresses: If the blister breaks out, saline, boric acid solution can be used externally, which can relieve local symptoms and avoid excessive exudation. 2. Topical medication: antiviral treatment with topical penciclovir, acyclovir, etc. If combined with bacterial infections, antiviral treatment with topical mupirocin ointment can be used. 3. Oral medication: If the systemic symptoms are more serious and the skin lesions are more frequent, oral antiviral medication, such as vasiclovir and penciclovir, can be taken. The above medications should be used under the supervision of a physician. If the symptoms are severe, the patient should go to the hospital in time.