Whether iliotibial bundle syndrome can be self-healed depends on the patient’s condition. For those with mild spasm of the iliotibial bundle, it can be self-healed through functional stretching exercises, while those with severe spasm cannot be self-healed and need to be treated with medication or surgery. 1. Mild symptoms: It can be gradually cured by proper knee stretching exercises and rest to improve the tension and thickening of the iliotibial bundle. 2. Severe symptoms: If the spasm of iliotibial bundle leads to local inflammation and exudation, thickening and contracture of iliotibial bundle leads to pain, oral non-steroidal anti-inflammatory drugs, such as ibuprofen or celecoxib can be used for pain relief, which can reduce swelling and pain. Minimally invasive arthroscopic treatment is chosen for severe cases. If there is iliotibial bundle syndrome, it is recommended to go to the hospital in time, follow the doctor’s instructions for standardized treatment, do not self-medication.