The knee effusion needs to be relieved according to its causes, such as acute effusion of the knee joint, gout, rheumatoid arthritis, and villous nodular synovitis of the knee joint, and general treatment, physiotherapy, medication, and surgical treatment can be taken after a clear diagnosis is made. 1. Acute knee joint effusion: Acute arthritis, knee cold, overwork and other factors will cause acute knee joint effusion, treatment can choose physical therapy, such as hot compresses, infrared therapy, microwave physiotherapy, etc., and with celecoxib, ibuprofen and other drugs to relieve pain. If there is more fluid, you can choose puncture drainage. 2. Gout: Acute attack of gout can also lead to knee effusion, you can choose to take uric acid-lowering drugs, such as febuxostat, colchicine, to control uric acid level. 3. Rheumatoid arthritis: Rheumatoid arthritis caused by knee effusion, can follow the doctor’s advice to take prednisolone treatment. If the amount of fluid is large, puncture drainage can be performed. 4. Synovitis of the knee joint with villous nodularity: knee effusion caused by synovitis of the knee joint with villous nodularity requires knee surgery to remove the diseased synovial membrane. The causes of knee effusion are very many, after the symptoms, it is recommended to go to the hospital in a timely manner to improve the examination, follow the doctor’s instructions to take standardized treatment, do not use drugs indiscriminately, so as not to lead to adverse consequences.