Stool with fresh blood, indicating that the bleeding site in the anal canal or rectum, accompanied by pain, the most likely due to anal fissure or hemorrhoids. It is necessary to consult a doctor in time for examination and treatment. 1. Anal fissure: the common clinical manifestations of anal fissure patients have severe pain during defecation, bleeding, constipation and other typical symptoms. The diagnosis can be made by perfect anal visualization and finger-pointing. Conservative treatment is the main treatment, such as 1:5000 potassium permanganate water sitz bath, local analgesic drugs such as lidocaine gel and so on to smear the affected area. If the effect of conservative treatment is not good, surgery can be used. 2. Hemorrhoids: Hemorrhoids are divided into internal hemorrhoids, external hemorrhoids, mixed hemorrhoids. Fresh blood in the stool, pain is considered to be mixed hemorrhoids, or internal hemorrhoids embedded. Can perfect anoscopy, anal finger test clear diagnosis. Treatment is based on surgery, such as external hemorrhoid stripping internal hemorrhoid ligation. The abnormalities of the stool may be caused by rectal cancer, sinusitis, anal fistula and other diseases. It is recommended to consult a doctor as soon as possible, improve the examination, and follow the doctor’s instructions to be treated accordingly after a clear diagnosis.