Trazodone treatment for insomnia is best given as a slow dosage according to the patient’s condition, and may need to be combined with benzodiazepines for patients with refractory insomnia.
Trazodone is a pentazocine blocking and reuptake inhibitor, suitable for patients with depression accompanied by anxiety, agitation, insomnia, has a strong sedative effect, and is also commonly used in the treatment of primary and secondary insomnia in clinical practice.
Trazodone for the treatment of insomnia, the starting dose of 25 ~ 50mg, the evening meal, because of the emergence of tolerance, usually need to be increased to 50 ~ 100mg per day according to the patient’s situation, but for some special patients the drug dose may need to be increased to the antidepressant amount of the range of 150 ~ 400mg per day.
For patients with persistent insomnia, trazodone may be used in combination with benzodiazepine sedative-hypnotic drugs.
Common adverse reactions to the use of this drug are drowsiness, occasional skin irritation, blurred vision, constipation, dry mouth, hypertension or hypotension, and tachycardia. It is contraindicated in people who are allergic to the drug, patients with severely impaired liver function, severe heart disease, cardiac arrhythmia and acute disorders of consciousness.
Trazodone treatment of insomnia needs to be standardized in the assessment of the physician to use, individualized treatment is the best treatment.