Whether autoimmune liver needs long-term medication depends on the patient’s condition. If the patient’s condition is mild and the medication is effective, the medication can be stopped after the condition is stabilized; on the contrary, long-term medication is needed. 1. Autoimmune liver, also known as autoimmune liver disease, is a kind of liver and gallbladder damage disease caused by the abnormalities of the body’s immune system due to various factors such as heredity, environment, and bad life habits. Patients may have symptoms such as fatigue, itchy skin, loss of appetite and jaundice. 2. Autoimmune liver disease usually needs to take prednisone and other glucocorticoid drugs, azathioprine and other immunomodulators, ursodeoxycholic acid and other choleretic drugs and other drugs for treatment. Whether autoimmune liver disease needs long-term medication is related to the patient’s condition, personal constitution and other factors. 3. If the patient’s condition is mild and the drug treatment effect is good, the drug dosage can be gradually reduced after the condition is stabilized, or even stop taking the drug. If the patient’s condition is serious, easy to relapse after stopping medication, or prone to autoimmune diseases, long-term medication is needed. Patients with autoimmune liver disease are advised to consult a doctor in time and actively receive treatment. Drugs should be used in strict accordance with the doctor’s instructions, and should not be used on their own, so as not to delay or even aggravate the condition.