Direct bilirubin 7.1umol/L, high, consider and liver disease related, such as physiological factors, viral hepatitis, cirrhosis and so on. 1. Physiological factors: for example, newborns may have high direct bilirubin 7.1umol/L because of their own metabolic characteristics, such as excessive bilirubin production, increased bilirubin reabsorption, etc. Most of them will recover on their own, and don’t need special treatment. 2. Viral hepatitis: For patients with viral hepatitis, there are often nausea, fatigue, loss of appetite and other related symptoms, and all major viral hepatitis are infectious, patients usually have high direct bilirubin when examined. 3. Cirrhosis: when the patient has cirrhosis, often there will also be high direct bilirubin performance, this kind of patients with early symptoms are more hidden, not easy to be detected, and in the late stage there will be jaundice, ascites, liver enlargement, endocrine dysfunction and so on. It is recommended that patients should pay attention to this problem, and if the cause cannot be determined by themselves, they need to go to the hospital and cooperate with the doctor to improve the examination before treatment.