Anomalous breast development is a semicircular mass that occurs in the areola, like a go-go piece buried in the areola, and can occur in both men and women, mostly in women during puberty. Under normal circumstances, male breasts do not develop. When the estrogen level in the body is relatively or absolutely increased due to various causes, and the mammary epithelial cells are stimulated by too much estrogen, very few men can have unilateral or bilateral breast enlargement, which is called male breast abnormal development. 1, the etiology of gynecomastia Male breast enlargement is called gynecomastia. The pathological manifestations are ductal hyperplasia without alveolar hyperplasia, which can be generally divided into two categories: primary and secondary, usually in adolescent boys and older men, mainly due to a transient rise in endogenous estrogen or a fall in androgens, which can often subside on their own, and secondary, commonly due to liver disease, testicular disease, adrenal gland disease, thyroid disease, diabetes and Secondary cases are often caused by liver diseases, testicular diseases, adrenal diseases, thyroid diseases, diabetes, tumors of the genitourinary system or nervous system, prostate diseases, long-term use of estrogen, or long-term use of other drugs such as reserpine, remifentine, digitalis, chlorpromazine, etc., which can also cause breast development, and can generally subside after stopping the drugs. In addition, hermaphroditism, congenital testicular dysplasia, will also lead to breast enlargement. 2, the clinical manifestations of gynecomastia This disease can be seen at all ages, breast development is about 60-80% bilateral symmetrical or asymmetrical, there are also unilateral development (more common on the left than on the right), its breast development performance varies in size, the two breasts are often seen asymmetrical or symmetrical bulge, small only in the areola subcutaneous can be palpable flat round nodules, hard and tough texture, clear edges, neat, good mobility, and In small cases, only flat round nodules are palpable under the skin of the areola. If an eccentric round lump is found, other lesions should be considered, clinically this lump is called ‘adenoma type’, another part of the developing breast with unclear edges is diffusely hyperplastic, often fused with the surrounding breast tissue, and no obvious nodules are palpable under the areola, the larger ones can gradually bulge like the size of a female breast, clinically this type is called ‘ This type is clinically referred to as ‘diffuse’ and the developing breast may often have a swelling sensation, or tingling, throbbing pain, and if there is an obvious nodule, there may often be pressure or tenderness, but painless cases are rare. A few patients squeeze the nipples with white milk-like discharge, and self-inflicted overflow is rare. 3, how to treat gynecomastia Men who find themselves with breast enlargement, should go to the hospital as soon as possible to confirm the diagnosis, if it is physiological, pharmacogenetic, it is not necessary to be too nervous, can subside on its own or after the withdrawal of drugs, if it is pathological, should be seriously looking for the cause and for the cause of timely treatment, male breast enlargement, at an earlier time that is given active and effective treatment, can still return to normal, and time The most important thing is that you can get a good idea of what you want to do. At present, Western medicine does not have a practical treatment for this disease, mainly using hormones to testosterone or estrogen receptor antagonist antagonism treatment and surgical removal, but for the surgical removal of easy to leave the ectopic scar, both affect the aesthetic and easy to recur. At present, surgery is not used, except in cases where the breast is too large, distended and painful, and even causes mental anxiety, while medication is ineffective, and the patient insists on having the surgery done. In addition, gynecomastia, due to its complex etiology, has different treatments for different causes. Patients with primary gynecomastia in adolescence have a tendency to heal themselves, usually returning to normal within 6 months.