Timosartan and captopril should not be taken at the same time. Timosartan is an angiotensin receptor antagonist, while captopril is an angiotensin-converting enzyme inhibitor, the pharmacological effects of the two drugs are relatively close to each other, and taking them at the same time will not produce synergistic effects, and may increase the side effects of the drug, increasing the incidence of adverse reactions. When taking timosartan to control blood pressure, there may be dizziness, headache and abdominal distension and other uncomfortable symptoms, while the use of captopril may be stubborn dry cough symptoms, must be under the guidance of a doctor to use the correct medication, if you can not tolerate the adverse effects of the drug, you need to consider switching to other types of blood pressure medication. The contraindications of the two drugs are similar, allergy to drug components, severe renal function abnormalities, hyperkalemia, pregnancy, bilateral renal artery stenosis and other conditions are prohibited. Although timosartan can not be taken at the same time as captopril, it can be combined with other antihypertensive drugs such as nifedipine or hydrochlorothiazide, respectively, and needs to be taken regularly as prescribed by the doctor in order to have a better antihypertensive effect.