Differential diagnosis of markedly elevated serum testosterone concentration

During the follicular phase of the normal menstrual cycle, the average serum testosterone concentration is 0.43 ng/ml, with a high limit of 0.68 ng/ml. If it exceeds 0.7 ng/m1 (equal to 2.44 nmol/L), it is called hypertestosteronemia, or hyperandrogenemia. The ovaries and adrenal cortex can synthesize cholesterol from acetic acid or absorb cholesterol from the blood as a substrate to synthesize steroid hormones, which are secreted into the blood circulation. The main androgens in the circulation are dehydroepiandrosterone sulfate (DHEAS), dehydroepiandrosterone (DHEA), androstenedione (Δ4A), testosterone (T) and dihydrotestosterone (DHT). Hypertestosteronemia is the result of high levels of these hormones, especially testosterone, in the blood. When it is elevated for some reason, it can increase the excretion of calcium by the kidneys and lower the blood calcium concentration. Calcitonin is a tridodecapeptide containing a disulfide bond with a molecular weight of 3400. serum calcitonin concentration in normal human is 10-20ng/L, with a plasma half-life of less than 1h, and is mainly degraded and excreted in the kidney. The main effect of calcitonin is to lower blood calcium and blood phosphorus, and its main target organ is bone, and it also has a certain effect on kidney. Low serum testosterone levels: The impact of hypogonadism and reduced testosterone levels on men’s health has been a controversial issue. Although studies have confirmed that high doses of testosterone or other exogenous androgen intake can be detrimental to health, low serum testosterone levels may predict increased mortality in older men. Low testosterone levels in blood may actually be a risk factor for coronary atherosclerosis. Testosterone, also known as testosterone, testosterone or testosterone, is a steroid hormone that is secreted by the testes in men or the ovaries in women, and to a lesser extent by the adrenal glands. It is the main male sex hormone and anabolic hormone. The amount of testosterone secreted by adult males is 20 times greater than that secreted by adult females. The average serum testosterone concentration during the follicular phase of the normal female menstrual cycle is 0.43 ng/ml, with a high limit of 0.68 ng/ml.