Sodium valproate and risperidone have a synergistic effect when used together. Sodium valproate is an antiepileptic medication that can be used to treat types of epilepsy such as petit mal, restrictive, grand mal and mixed epilepsy and disorders such as febrile convulsions (convulsive seizures due to hyperthermia), chorea, and schizophrenia. Risperidone is an atypical antipsychotic medication that can be used to treat symptoms such as anxiety, delusions, disordered thinking, and depression caused by schizophrenia and other psychoses. Sodium valproate and risperidone are synergistic in treating acute manic or mixed episodes. However, sodium valproate may cause gastrointestinal symptoms, liver function impairment, dizziness, headache, tremor and other side effects; risperidone may cause insomnia, anxiety, dizziness, muscle tension and other side effects taking at the same time may lead to superimposed side effects. Therefore, it is not recommended to take the drug by yourself, and it is recommended to use it at the same time under the guidance of a doctor.