Indirect bilirubin 60umol/L is not serious if it is physiological jaundice of newborn, but if it is caused by hepatocellular factor, hemolytic factor, congenital jaundice, etc., it needs to be treated as soon as possible so as not to miss the condition. 1. Physiological jaundice of newborns: physiological jaundice formed after the birth of children, resulting in indirect bilirubin 60umol/L, most of which can gradually return to normal and not serious. 2. Hepatocellular factor: common in acute hepatic necrosis, acute jaundice hepatitis, cirrhosis and other diseases lead to low amount of hepatocytes, hepatic function decreases, which causes the liver’s indirect bilirubin uptake and excretion to be impaired. 3. Hemolytic factors: Indirect bilirubin 60umol/L caused by congenital hereditary red blood cell abnormality, bead protein production disorder anemia is more serious. Indirect bilirubin 60umol / L, if excluded from the physiological jaundice in newborns, it is recommended to consult a doctor in a timely manner to identify the cause of the early treatment, so as not to delay the condition.