Commonly used painkillers in orthopedics include Celecoxib, Diclofenac Sodium, Loxoprofen Sodium, Meloxicam, Etoricoxib and so on. 1. Celecoxib: It can be used to treat the signs and symptoms of acute or chronic osteoarthritis and rheumatoid arthritis. 2. Diclofenac sodium: the drug can be used to relieve rheumatoid arthritis, osteoarthritis, can also be used for gouty arthritis, rheumatoid arthritis, spondyloarthropathies and other chronic arthritis in the acute attack or persistent joint swelling and pain. It can also be used in the treatment of tenosynovitis, bursitis myalgia, shoulder pain, pain after exercise injury and other soft tissue rheumatic pain, but also can be used for trauma, pain after strain. 3. Loxoprofen sodium: commonly used in the treatment of rheumatoid arthritis, neck-shoulder-wrist syndrome, osteoarthritis, periarthritis of the shoulder joint, lumbago, and anti-inflammatory and analgesic dental pain. It can also be used for anti-inflammatory and analgesic after surgery and tooth extraction, as well as antipyretic and analgesic for acute respiratory tract infection. 4. Meloxicam: It is noted to improve the symptoms of rheumatoid arthritis and painful osteoarthritis. 5. Etoricoxib: The drug can treat the signs and symptoms of osteoarthritis in the acute and chronic phases, as well as acute gouty arthritis and primary dysmenorrhea. Patients are advised to choose reasonable painkillers for treatment according to their own conditions and after assessment by their doctors.