Azithromycin should not be taken by patients who are allergic to azithromycin, patients whose past use of azithromycin resulted in cholestatic jaundice, or patients with a history of hepatic insufficiency. 1. Allergy: patients known to be allergic to azithromycin or allergic to erythromycin or roxithromycin are advised not to take azithromycin, and there is cross allergy to macrolides. 2. Patients with cholestatic jaundice due to previous use of azithromycin: If cholestatic jaundice has occurred after previous use of azithromycin exists, this drug should not be taken. 3. History of hepatic insufficiency: Azithromycin should also not be taken if there is a previous presence of hepatic insufficiency. In addition, pregnant women, lactating women, the elderly, children or patients taking other drugs, before using Azithromycin should be informed of their own situation in advance or under the guidance of a physician to use, not blindly self-medication.