Trimipramine, which is known by the trade name Daphylline, costs about$2,000 a pop and is used clinically for the treatment of precocious puberty, uterine fibroids and endometriosis. It is used more often for the treatment of endometriosis, mainly to counteract estrogen so that amenorrhea occurs clinically. Once amenorrhea occurs, the lesions of endometriosis will no longer experience cyclic bleeding, so the purpose of treatment will be achieved. When amenorrhea occurs during the medication period, care should also be taken to exclude whether the amenorrhea is caused by pregnancy, as this is especially important because of the possibility of pregnancy after the ectopic lesion is controlled. It is recommended to always use good contraception if you have sexual intercourse during the medication.