Nine-valent vaccine is not recommended during a runny nose. Nine-valent vaccine generally refers to the nine-valent HPV vaccine, which can be used to prevent human papillomavirus (HPV) infection and cervical cancer caused by infection. Adverse reactions such as dizziness, nausea, vomiting, drowsiness, hot flashes, migraines, menstrual cramps, fever, limb discomfort, and urticaria can occur after receiving this vaccine. Patients with runny nose symptoms, indicating that in the upper respiratory tract infection period, when the patient’s body immunity is relatively low, and vaccination with the nine-valent vaccine, may aggravate the adverse reactions or affect the immune effect, it is recommended that patients wait until the symptoms are relieved and then vaccinate with the nine-valent HPV vaccine. And if you are taking medication, you can stop taking it for a week or so before taking the vaccine, so as not to affect the effect of the vaccine. For more information about the HPV vaccine, patients are advised to consult the local vaccination department and learn about the contraindications and adverse reactions.