There are genetic factors involved in Alzheimer’s, but it is not a certainty that the disease will develop, and regular medical checkups can help with early detection and early intervention. A positive family history of Alzheimer’s increases the incidence of Alzheimer’s disease, but an increased incidence does not necessarily mean that the disease will develop. The development of Alzheimer’s disease is now strongly associated with three factors, including increasing age, a positive family history, and the ApoE genotype. Therefore, the development of Alzheimer’s disease is closely related to multiple factors and is not determined by a single factor. Therefore, elderly people, people with positive family history, and ApoE-positive patients should have regular medical checkups and pay attention to the presence of early symptoms of Alzheimer’s disease, and come to the hospital in time if there are any.