Palm hard edema is palm tissue due to trauma, infection, autoimmune factors such as inflammation and local edema, due to a variety of reasons, some of the edema will continue for more than a month to 1-2 years, we will be post-injury edema lasts more than 6 weeks without subsiding tendency of the person is called “persistent edema,” which in some cases, edema fluid is rich in protein, will gather a lot of fibrin, together with the inflammatory hyperplasia to cause scar tissue formation, making the skin, subcutaneous hardening. “In some cases, the edema fluid is rich in protein, which will gather a lot of cellulose, and inflammatory hyperplasia together with the formation of scar tissue, so that the skin, subcutaneous hardening. This is the formation of “sclerosing edema.” Palm hard edema symptoms are caused by how? 1.Lymphatic primary lymphedema (congenital lymphedema, early onset lymphedema), secondary lymphedema (tumor infection, surgical radiation, etc.). 2, venous obstruction tumor compression or tumor metastasis, local inflammation venous thrombosis, thrombophlebitis, scar contraction and trauma. It can be divided into chronic venous insufficiency, superior vena cava obstruction syndrome, inferior vena cava obstruction syndrome and other venous obstructions. 3.Poisoning, boils, snake venom, poisoning and so on. 4.Anaphylactic urticaria, serum sickness, and food and drug irritation, allergic reactions to topical medications. 5.Vascular neurogenic can be allergic reaction or neurogenic can be triggered by mechanical stimulation of insects, warm and hot stimulation or emotional excitement. Some cases are related to heredity. 6.Trauma, stress, etc. 7.Kawasaki disease.