The fiery pain in the nose is considered to be related to dry environment, boils, colds, acute nasal vestibulitis and other diseases, which need to be treated with moisturizing environment, topical or oral medication according to the cause. 1. Dry environment: If the environment is dry, especially in the fall, and if you don’t drink enough water, it may lead to fiery pain in the nasal cavity. This condition can be relieved by adding a humidifier and drinking more water. 2. Boil: It is a purulent inflammation of a single hair follicle and its surrounding tissues, mostly caused by Staphylococcus aureus. This condition can be treated with topical ichthyol ointment, tincture of iodine, mupirocin ointment, etc. It can also be treated with oral amoxicillin, cefixime and other medications. 3. Colds: Colds can cause nasal congestion, runny nose, cough and other symptoms, the patient will feel the nose hot and painful. In this case, you can use saline to clean the nasal cavity, oral pseudoephedrine hydrochloride and other drugs. 4. Acute nasal vestibulitis: diffuse inflammation of the nasal vestibular skin, the patient will also appear nose hot and painful. This situation can be treated with saline cleaning of the nasal cavity, applying antibiotic ointment, oral antibiotics (amoxicillin, cefixime) and other drugs. There may be other reasons for the burning pain in the nose, and it is recommended to seek medical attention to identify the cause and then target treatment.