Niacinamide is effective in the treatment of certain skin diseases such as dermatophytosis, and is used clinically to prevent and treat dermatophytosis combined with stomatitis, glossitis, sick sinus node syndrome, atrioventricular block and so on. Niacinamide is also effective in the treatment of acne, with antibacterial and anti-inflammatory effects, and can control the secretion of the sebaceous cortex to reduce pores. It also has a good whitening effect on the skin, promoting collagen synthesis and preventing excessive melanin deposition. In addition it is good for maintaining the integrity of normal tissues, especially skin tissues, because niacinamide is a component of Coenzyme I and Coenzyme II.