The most common bacterial infections are common causative factors of acute urinary tract infections, which often cause an increase in leukocytes in urine, and the common bacteria are mainly Escherichia coli, Proteus mirabilis, Staphylococcus, etc. The route of infection is mainly retrograde transmission through the urethra. In addition, specific inflammation of the urinary system can also cause increased leukocytes in the urine, such as urinary tuberculosis is also a common cause of increased leukocytes. Some atopic cystitis, such as interstitial cystitis, glandular cystitis, and radiation cystitis, and other specific inflammatory conditions, can also cause increased leukocytes in the urine. Patients with high leukocytes can have further tests to clarify the specific cause and then choose a reasonable treatment plan to treat it.