After cardia resection, you should decide whether to take omeprazole for a long period of time based on the postoperative symptoms, and you should be aware of any adverse drug reactions. The main function of the cardia is to prevent gastric contents from refluxing into the esophagus when the stomach is peristaltic, so when the cardia is removed symptoms such as acid reflux, heartburn and belching (burping) can occur. Omeprazole has the effect of inhibiting the secretion of gastric acid, which can reduce the reflux, so you can take Omeprazole if you have complications such as acid reflux for a long time. However, it should be noted that adverse reactions such as headache, abdominal pain, flatulence and diarrhea may occur when taking omeprazole, which can usually disappear after stopping the drug. If the symptoms do not improve after taking the drug or long-term adverse reactions, it is recommended to go to the hospital in time to check and change the drug.