Tuberculosis adverse reaction is too large when it is recommended to stop the drug, timely go to the hospital for relevant examinations, and under the guidance of the doctor to choose the less adverse reaction of the drug instead of for treatment. If an allergic reaction occurs, anti-allergic drugs can be taken for treatment. When the human body is infected by Mycobacterium tuberculosis, it may lead to fever, cough, sputum, frequent urination, urinary urgency, fatigue and other symptoms. Anti-tuberculosis drugs may be taken for treatment. Some patients may experience adverse reactions such as rash, itching, low fever, nausea, vomiting and decreased appetite when taking anti-tuberculosis drugs for treatment. If the above adverse reactions are too great, the patient should stop taking the anti-tuberculosis drugs in time and go to the hospital in time for relevant examination and symptomatic treatment with the specific symptoms of the patient. And under the guidance of the doctor to choose the less adverse reaction of the drug instead of treatment, such as streptomycin sulfate tablets, ethambutol hydrochloride tablets, isoniazid tablets and so on. If there is a large allergic reaction can take anti-allergic drugs for treatment, such as loratadine tablets, cetirizine tablets, chlorpheniramine maleate tablets and so on. Tuberculosis treatment adverse reaction is too large patients should be timely to the hospital for relevant examinations, combined with the patient’s specific situation under the guidance of the doctor for medication and treatment.