Impetigo can be incised and drained, but mainly for patients with deep impetigo. Impetigo is a contact infectious bacterial infection. Incision and drainage surgery for impetigo is mainly for patients with deep impetigo because the infection site is deep in the skin, and it is more difficult to drain the pus. If the pustules are superficial, antibiotic ointment such as mupirocin or fusidic acid can be applied externally, and the pustules can gradually subside, and oral antibiotic treatment can be taken if necessary. It should be noted that after surgical drainage of pus, it is necessary to apply povidone-iodine or alcohol to disinfect, and apply topical medication under doctor’s guidance, and then use sterile gauze for bandaging, and change the medication every 3 to 5 days, if the situation is serious, it is necessary to follow the doctor’s instructions to use antibiotics for follow-up treatment. Impetigo incision and drainage surgery must be carried out in a regular hospital, followed by regular treatment, can avoid the re-emergence of bacterial infection.