There is no such thing as “medicine that really works for constipation”, and the current medicines for constipation mainly include volumetric laxatives, stimulant laxatives, lubricating laxatives, osmotic laxatives, and so on. 1. Volumetric laxatives: if the gum, lactulose, plant fiber, etc., side effects are smaller, the current clinical use of more, can change the stool properties, increase the water and volume of stool to achieve the effect of laxative. 2. Stimulating laxatives: such as castor oil, bisabolol, etc., can stimulate intestinal peristalsis to relieve the symptoms of constipation. However, they are not suitable for long-term use, and long-term use can lead to side effects such as colorectal melanosis. 3. Lubricating laxatives: such as mineral oil, corkscrew or liquid paraffin, with lubrication of the intestinal wall, soften the role of stool. Again, it is not suitable for long-term use, otherwise it is easy to lead to intestinal dependence and other side effects. 4. Osmotic laxatives: such as polyethylene glycol, sorbitol, etc., can be used as fecal impaction or as temporary medication for chronic constipation, not to be used regularly, and overdose is prone to electrolyte disorders and other adverse reactions. 5. Other: such as pro-dynamic drugs, Prucalopride, Rubiprost, linaclotide, intestinal probiotics can regulate intestinal dynamics and intestinal flora, play a role in relieving constipation. The above drugs should be used in accordance with medical advice. It is recommended that patients with constipation first go to the hospital for consultation and standardized treatment under the guidance of a doctor.