What are the side effects of using laxatives for chronic constipation?

Long-term constipation using laxatives, lactulose, polycarbophil calcium, etc., may have side effects that lead to intractable constipation, water-electrolyte disorders, osteoporosis and other conditions.
1. Persistent constipation: long-term use of laxatives will reduce the sensitivity of the intestinal wall to feces, thus causing persistent constipation. Some laxatives, such as calcium polycarbophil, are not easily absorbed by the intestinal wall and tend to accumulate and produce a continuous effect leading to an increase in the amount of stool, and if the patient drinks less water, it can also cause persistent constipation.
2. Water electrolyte disorders: the use of lactulose and other laxatives will lead to a large amount of water and electrolyte loss in the patient’s body, long-term use may cause hyperkalemia and other electrolyte disorders.
3. Osteoporosis: if the patient long-term use of lubricating laxatives, such as glycerin, may cause intestinal absorption disorders, leading to osteoporosis and other vitamin absorption disorders.
If the patient has long-term constipation, it is recommended to consult a doctor in a timely manner, to clarify the condition of the corresponding treatment, the drug should be used under the guidance of a doctor, so as not to cause adverse reactions.