Abnormal prothrombinogen is also known as abnormal coagulation factor II. A slow rise in abnormal coagulation factor II may be due to vitamin K deficiency, chronic liver disease and liver cancer.
1. Vitamin K deficiency: Vitamin K is an auxiliary agent for synthesizing coagulation factor II. When vitamin K is deficient, the human body cannot synthesize coagulation factor II normally, and a slow rise of abnormal coagulation factor occurs.
2. Chronic liver disease: Chronic liver disease will lead to decreased synthesis of coagulation factors by the liver, which can only synthesize abnormal coagulation factors, and then abnormal coagulation factor II will be elevated.
3. Hepatocellular carcinoma: patients with hepatocellular carcinoma have abnormal prothrombin, and pre-prothrombin carboxylase principle cannot be fully utilized, which will lead to the production of a large amount of abnormal prothrombin Ⅱ, and there will be a situation that the indexes are slowly elevated.
There may be other reasons for the slow rise of abnormal coagulation factor II. It is suggested that patients should consult the doctor in time and receive diagnosis and treatment under the guidance of the doctor.