Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that can involve multiple organs and systems such as skin and mucous membranes, skeletal muscles, kidneys, central nervous system, lungs, heart and blood, etc. The clinical manifestations are complex; multiple autoantibodies and immunological abnormalities can be detected in the serum. 1.Keep a comfortable mood, treat the disease correctly and cooperate with the treatment. Pay attention to the combination of work and rest, appropriate exercise, weather changes in time to add clothing, prevent colds. 2.Rationalize the diet and ensure comprehensive nutrition. Do not eat foods that enhance photosensitivity: such as figs, rape and celery, etc. Avoid sunlight after consumption. 3. Smoking cessation, weight reduction, appropriate exercise, blood pressure control and lipid monitoring can reduce the risk of cardiovascular disease in SLE. 4. Reduce sunlight exposure and avoid exposure to sunlight and ultraviolet radiation. Wear hats and long clothing for outdoor activities in summer. It is best to wash your face with warm water and avoid using make-up and alkaline soap. 5.Clean and hygienic residence, avoid cold and humidity, and minimize contact with plant and animal pathogens. 6, long-term application of glucocorticoids patients should be appropriate supplementation of calcium, vitamin D and bisphosphonates to prevent and treat osteoporosis. 7.When there is Raynaud’s phenomenon: avoid staying in the cold air for a long time in winter, adjust the thickness of gloves and socks according to the temperature change to maintain the temperature of the extremities; avoid entering the refrigerator directly to take things and avoid contact with cold water. 8, female patients pay attention to contraception, disease activity period, avoid pregnancy, should not take oral contraceptives containing estrogen. Those who wish to have children should be pregnant under the guidance of a doctor. 9.Adhere to the medication treatment under the guidance of the doctor, do not reduce the medication, reduce or increase the dosage without authorization. 10. If there are signs of disease activity (such as fever, fatigue, loss of appetite, joint pain, muscle aches, general discomfort, weight loss, rash, hair loss, headache, chest pain, dry mouth and eyes, mouth ulcers, swollen lymph nodes, purpura, swelling, etc.), you should consult a doctor promptly. 11.If the disease starts within six months, it is best to follow up once a month. After the disease has stabilized, regular blood and urine tests and immunological measurements should be performed at least once every three months to understand the changes in the disease.