SLE is a diffuse, systemic autoimmune disease, mainly involving the skin and mucous membranes, skeletal muscles, kidneys and central nervous system, but also many organs and systems such as lung, heart and blood, showing a variety of clinical manifestations; a variety of autoantibodies and immunological abnormalities can be detected in the serum. I. Dietary guidance 1. Dietary principles: Due to the prolonged use of hormones, application of immunosuppressants and other drugs, the resistance of the body of SLE patients is reduced, therefore, the adverse dietary habits that are not conducive to the disease should be changed, and a high-calorie, high-vitamin, low-salt diet should be given in the diet. 2, dietary contraindications: figs, rape, celery, mushrooms, shiitake mushrooms, etc. can cause photosensitivity, facial erythema, rash, etc. Therefore, SLE patients with photosensitivity do not eat or eat less food with enhanced photosensitivity, such as renal impairment, should be supplemented with sufficient high-quality protein. Mutton, dog meat, horse meat, donkey meat, venison, etc. are warm and hot in nature, which will aggravate the internal heat symptoms of SLE patients after consumption. Chili, green pepper, garlic, onion, leek, cinnamon and other overly hot foods should not be eaten more or often. For patients who take hormones for a long time and cause high blood fat and high blood sugar, pay attention to eat less food with high fat and cholesterol content and high sugar food. It is not advisable to drink alcohol and smoke. The harmful components in cigarettes such as nicotine can stimulate the walls of blood vessels and aggravate vasculitis. Patients with lupus nephritis should supplement high-quality protein, such as milk, eggs, lean meat, fish and other animal proteins, because of long-term protein loss from urine, which reduces albumin in the body. Patients are prone to infection and should avoid frequenting public places with large crowds to reduce the contact with pathogens. Maintain appropriate temperature and humidity in the patient’s room, disinfect the air on time, and open windows daily to maintain indoor air circulation. Avoid using irritating or allergic cosmetics, including creams, hair dyes, etc. Develop good hygiene habits and keep your mouth clean. Avoid sun exposure, avoid exposing the skin to sunlight in ways such as avoiding going out between 10 a.m. and 3 p.m. when the sun is stronger, prohibiting sunbathing, wearing long-sleeved tops and long-legged pants, umbrellas, sun shades and sun hats when going out in summer to avoid causing photoallergy and aggravating the rash. Glucocorticoids and immunosuppressants are the first choice for the treatment of SLE. Blood pressure, blood sugar, electrolytes, liver and kidney functions should be monitored regularly during the course of medication. Avoid taking drugs that can induce SLE, such as hydrazinepyridazine, procainamide, isoniazid, chlorpromazine and methyldopa. Most SLE patients are women of childbearing age. Pregnancy can trigger SLE activity, especially in early pregnancy and 6 weeks after delivery, so the number of pregnancies should be reduced as much as possible, and pregnancy should be avoided during the non-remission period otherwise miscarriage, preterm delivery, stillbirth and aggravation of SLE may occur. In recent years, many scholars believe that when the dosage of prednisone is controlled below 10 mg per day, patients who have been in remission for more than six months can be safely pregnant under the guidance of a doctor without serious damage to other organs. In the first 3 months and the last 3 months of pregnancy should be closely observed, consult the hospital at any time, and avoid breastfeeding after delivery to ensure the safety of mother and child. V. Activity guidance For patients in the acute active stage, they must rest strictly in bed and maintain good posture and functional position of joints, and actively cooperate with treatment. Ensure sufficient sleep. When the condition is stable, patients in remission can arrange health care and strengthening activities in an appropriate amount, and carry out activities appropriately within the scope of physical strength, and arrange their life and work time reasonably. You can choose some easy exercise items such as walking, jogging, cycling, qigong, taijiquan, etc. Moderate activities are beneficial to patients’ emotional improvement, promote mental health and enhance self-confidence. It is important to avoid strenuous exercise and prevent overexertion.