Numbness or burning pain in the fingers after sleep that causes waking is one of the symptoms of carpal tunnel syndrome. The pain and sensory numbness in the thumb, index and middle finger are caused by compression of the median nerve. Initially, it is often characterized by sensory dysfunction in the fingers, and often wakes up with numbness or burning pain several hours after falling asleep, which is relieved by activity. Many diseases can present with symptoms similar to those of carpal tunnel syndrome, such as numbness and pain in the fingers. Therefore, attention should be paid to differentiation to prevent misdiagnosis. So, what tests can be done to confirm the diagnosis of numbness or burning pain in the fingers after sleep? The following are the tests that need to be done to detect numbness or burning pain in the fingers after sleep: If carpal tunnel syndrome is suspected, the following tests should be performed to clarify the diagnosis: 1. Tinel’s sign: If the thumb, index and middle finger have radiating pain when tapping the median nerve at the proximal edge of the carpal ligament, the test is positive. 2. Wrist flexion test: rest both elbows on the table, forearms perpendicular to the table, and both wrists are naturally palmarly flexed. At this point, the median nerve is pressed against the proximal edge of the transverse carpal ligament, and pain soon appears in those with carpal tunnel syndrome. 3.Cortisone test: Inject hydrocortisone into the carpal tunnel, if the pain is relieved, it will help to confirm the diagnosis. 4, Tourniquet test: inflate the sphygmomanometer to above the systolic pressure for 30-60 seconds that can induce finger pain is positive. 5.Wrist extension test: maintain the wrist in the hyperextended position, and if the pain appears soon, it is positive. 6.Finger pressure test: If finger pressure at the median nerve pressure point at the proximal edge of the transverse carpal ligament can induce finger pain, the test is positive. 7. Median nerve conduction speed: Normally, the conduction speed of the median nerve is shorter than 5 microseconds from the proximal transverse carpal ligament to the motor fibers between the thumb to palmar muscles or the thumb short extensor muscles. If it is longer than 5 microseconds, it is abnormal. Carpal tunnel syndrome of up to 20 microseconds indicates damage to the median nerve. Surgical treatment should be considered for conduction times greater than 8 microseconds.