There are many reasons for patients to have burning urethra, mainly including urinary tract infection, gonorrhea, urethral stones and so on. 1. urinary tract infection: urinary tract infection most often occurs in female patients, because women’s urinary tract is short, straight, more susceptible to infection by bacteria and other pathogenic microorganisms, one of the typical symptoms of urinary tract infection is burning sensation of the urethra during urination, in addition to the frequent occurrence of hematuria, urine output is reduced, and other symptoms. 2. Gonorrhea: a disease in which patients are infected with gonococcus bacteria mainly through sexual contact, gonococcal urethritis occurs most often in male patients, in which case the patient will experience burning sensation at the urethra when urinating. 3. Urethral calculi: The main source of urethral calculi is kidney and bladder stones, which are embedded in the urethra during urination, thus blocking the discharge of urine, and the patient will experience urinary pain and burning sensation of the urethral opening when urination is difficult. There may also be other reasons, it is recommended that the patient go to the hospital in time, improve the examination to clarify the cause of the disease, and then give targeted treatment or treatment.