In general, patients with hypertension can take painkillers, and severe pain can cause an increase in blood pressure. Patients with previous hypertension should avoid producing severe pain, which can lead to an increase in blood pressure, and if pain occurs in patients with hypertension and severe pain, they should take certain painkillers, such as non-steroidal anti-inflammatory drugs, which are common, such as diclofenac sodium or celebrex, fenbid, and Depo tablets, etc. These drugs do not fluctuate or affect blood pressure, and they have some anti-inflammatory effects and can be used for patients with hypertension. Pain medications such as tramadol have good central pain relief and are effective for moderate pain. Patients with hypertension can also be applied for the above mentioned central pain medications.