The appearance of small red spots on the calves of AIDS patients may be related to common warts, herpes zoster, Kaposi’s sarcoma and other causes. 1. Common warts: Due to the decreased immunity of AIDS patients, if they are infected by the human papilloma virus, pink or flesh-colored superfluous organisms can appear in the calf, causing the phenomenon of small red spots on the calf. 2. Herpes zoster: when the body’s immune system function decreases, the chickenpox-herpes zoster virus is activated again, and clustered blisters can appear in the calf, etc., and the phenomenon of small red dots appearing on the calf. 3. Kaposi’s sarcoma: the initial stage of the disease can be manifested as red or purple small papules, which gradually develops into enlargement, fusion into multiple spots, plaques or nodules, mostly seen in AIDS patients, so the initial stage of the disease can be in the phenomenon of small red dots on the lower legs. It is recommended that AIDS patients with small red spots on the calves go to the hospital in time to clarify the cause of the disease and carry out standardized treatment under the guidance of the doctor, so as not to delay the condition.