If this indicator is increased, it is mainly seen in the following two cases: 1. Malignant tumors, including pancreatic cancer, gastric cancer, colorectal cancer, malignant tumors of liver and biliary system, etc. Among them, the specificity of CA19-9 is stronger for pancreatic cancer, and 70% of pancreatic cancer patients will have increased indicator. Therefore, this index is often used as a specific tumor marker for pancreatic cancer; 2. In benign diseases, such as chronic pancreatitis, this index can also be increased, but the increase is generally small.