Vomiting and diarrhea gastrointestinal discomfort may be caused by acute gastroenteritis, or food poisoning. 1. Acute gastroenteritis. Acute gastroenteritis refers to the acute inflammation of the gastrointestinal mucosa caused by eating food contaminated by bacteria, viruses, parasites, or cold, irritating food, patients may experience stomach discomfort, diarrhea, nausea, vomiting and other symptoms, and in severe cases, fever, dehydration, electrolyte disorders, and even life-threatening. Through the perfect blood routine, stool routine and culture and other tests can assist in the diagnosis. 2. Food poisoning. Food poisoning is caused by eating food contaminated by bacteria, toxins and toxic substances, and the patient may also have vomiting and diarrhea with upset stomach. If the co-eaters also appear similar performance, should be highly suspicious of this disease, improve the blood routine, stool routine, etiology and toxin examination to clarify the cause of poisoning. Of course, this symptom may also be caused by other factors, if the symptoms continue to be unrelieved, especially when dehydration occurs, we should consult a doctor in time, cooperate with the doctor to improve the relevant examination, to clarify the cause of the disease, and cooperate with the doctor to actively treat the disease.