I have done two cases of anal fistula blocking treatment, which is my personal and real practice, not a fabrication. Both patients had high complex horseshoe fistulas, deep to the pelvic rectal fossa more than 12 cm from the external opening to the tip of the fistula and 8 cm from the anal verge, one had been operated on three times and one twice. Because of the hanging wire the anus had different degrees of deformity and slightly impaired function. The first surgery I performed was an incisional open-opposition drainage, after which I found that both were half healed, one on the right and one on the left. The other side formed a fistula about 8 cm long with an oblique curve. The difficulty of this second surgery was in front of us, and at this point, if the incision was made, the anal function would be compromised. If you do not open, the patient does not agree, the patient is heard that I have a level of reputation to come, do not beat the retreat will not be bad sign. Since the fistula was thoroughly explored during the first surgery and there was no branch tract, it was determined through analysis that the reason for the fistula not healing was poor drainage due to muscle tension. After thinking about it, we decided to use the adhesive plugging method, or blocking method. Since this was the first time this type of surgery was performed, it was a new technique and was filed with the medical department and the patient signed the consent. The fistula wall was scraped with a spatula to remove decayed necrotic tissue and edematous granulation to ensure a fresh and clean fistula wall, and then flushed with Anion iodine, followed by saline and blotted with gauze. Use bioprotein glue, domestic, sucked in two syringes, installed on the shelf, connected to the injection tube, scalp needle minus the needle, carefully placed on the top of the fistula, the assistant fixed, and the injection tube connected, slowly injected, when you see the glue flow, blocked with gelatin sponge, and pull out the injection strip while injecting, followed by blocking with gelatin sponge, do not make the glue flow, ten seconds after the glue solidified, but the gelatin sponge need not The gelatin sponge should not be removed, blocking the outer opening and fixed with gauze outside. After the operation, antibiotics were given. For fear of premature defecation after surgery, the glue was squeezed out and TPN was given for one week. The results were quite satisfactory and the fistulae were closed. By this time two extremely complicated anal fistulas were completely cured and have not recurred for a year and a half, and are not expected to recur. I had never done or seen anyone else do this type of surgery before, but had only heard that it could be done. I took the instructions for the bioprotein gel and read them over and over again, but there was only one sentence that said it could be used to treat fistulas. Then I thought that if other people can do it, then I can do it, and as for the specific operation, it is in line with the norms of anal fistula treatment. It is not a whimsy, but in accordance with the principles of medicine. It is in accordance with the principles of medical science. So the success of the surgery was not a fluke. The experience is that bioprotein gel sealing of fistulas, especially high-grade complex fistulas, is really feasible and can shorten the course of the disease and reduce the patient’s pain because there is no need for painful medication changes. The cost is also reduced. The key is that the function of the anal sphincter can be greatly protected. I hope that colleagues will criticize and share their experiences and opinions.