The treatments of high bilirubin in liver cancer include surgery, medication, local treatment and so on. High bilirubin in liver cancer patients is mainly considered as jaundice due to hepatocellular injury and obstructive jaundice due to tumor compression. In order to control jaundice and reduce bilirubin level, the following methods of treatment can be adopted. 1. Surgical treatment mainly includes external bile drainage surgery and biliary stenting surgery to drain bile, so as to improve biliary stasis caused by compression or tumor obstruction, which can be used to treat high bilirubin caused by obstructive jaundice. 2. Medications include liver-protecting drugs and bilirubin-lowering drugs. Liver-protecting drugs can restore the function of damaged liver cells, such as glutathione and diammonium glycyrrhizinate, etc. Bilirubin-lowering drugs can improve the high bilirubin situation, such as adenosylmethionine and ursodeoxycholic acid, etc. These drugs are mainly used to treat high bilirubin caused by damage to liver cells. 3. Local treatment mainly includes anti-tumor treatment such as radiotherapy. After the tumor shrinks, the pressure and obstruction on the bile ducts can be reduced, and the bilirubin level in the body can also be reduced. Patients should go to the hospital in time, under the guidance of the doctor, complete the relevant examinations, clarify the condition and give systematic and regular treatment.