Acute pharyngolaryngitis is very painful externally with pressure pain, and targeted treatment should be chosen based on the specific cause and degree of symptoms. Considering that there is submandibular lymph node enlargement, it is recommended to go to the hospital immediately to test the whole blood routine, according to the test results, if lymphocytosis is considered to be a viral infection, anti-viral treatment should be carried out. If it is neutrophilia, it is considered to be caused by bacterial infection, and antimicrobial treatment should be carried out. 1. Viral infection: antiviral drugs such as valaciclovir and ribavirin can be applied to carry out antiviral treatment, combined with dexamethasone to improve the symptoms of edema and congestion in the throat, and to alleviate the symptoms of pain caused by laryngitis. Cough with phlegm can be applied to expectorant aminoglutethimide. 2. Bacterial infection: acute pharyngolaryngitis is mostly caused by Staphylococcus aureus, Streptococcus aureus, S. pneumoniae infections, penicillin, cephalosporin antibiotics, antibacterial treatment. Do drug sensitivity test before use. And combine with dexamethasone to relieve the symptoms of edema and congestion in the throat. You can also use budesonide for local nebulization treatment to relieve pain symptoms. The above drugs should be used under the guidance of a doctor to ensure the safety of medication. Usually drink more water, eat a light diet, talk less, rest more, conducive to the recovery of the condition. Acute pharyngolaryngitis can cause respiratory distress, serious life-threatening, it is recommended to consult a doctor in a timely manner, as prescribed by the doctor for symptomatic treatment.