This is because the metabolism of fats in the body, including triglycerides, LDL cholesterol, HDL cholesterol and lipoproteins. In addition to being affected by the patient’s diet and exercise, it is also affected by the activity of fat metabolizing enzymes in the body. If you keep on exercising, you lose more weight than before, but because of disease or genetic mutation, the activity of the enzyme responsible for metabolism in the body is abnormal, which can also cause metabolic disorders in the body. It is necessary to check the activity of fat metabolizing enzymes in time, and it is better to do genetic testing. If the elevation of lipids is obvious, mainly triglycerides, you need to take beta drugs, including fenofibrate. If it is mainly cholesterol increase, you need to take statin drugs, such as atorvastatin, resuvastatin, and then check the blood lipid after half a month.